SCHEMBL30140765

SCHEMBL30140765

C=CCc1ccc(O)c(-c2cc(CC=C)ccc2OCC=C(C)C)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 10/20 0.67
GABRB2 P47870 10/20 0.67
CNR2 P34972 5/20 0.60
CNR1 P21554 3/20 0.60
ALDH1A1 P00352 3/20 0.60
MEN1 O00255 2/20 0.60
GAA P10253 2/20 0.60
MAPT P10636 2/20 0.60
KMT2A Q03164 2/20 0.60
PPARG P37231 2/20 0.60
PPARD Q03181 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH2 P05091 1/20 0.60
AKR1B1 P15121 1/20 0.60
HPGD P15428 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
ALOX5 P09917 6/20 0.54
CYP3A4 P08684 1/20 0.54
AR P10275 1/20 0.54
PTGS1 P23219 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31341318 1.00 GABRA1 (0.67) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL18838069 1.00 GABRA1 (0.67) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL31341380 0.88 GABRA1 (0.71) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL18838054 0.88 GABRA1 (0.71) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL525807 0.83 GABRA1 (0.74) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL23728222 0.83 GABRA1 (0.65) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL27405804 0.81 GABRA1 (0.74) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL525761 0.80 GABRA1 (1.00) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL20739713 0.80 ALDH1A1 (0.67) GABRA1GABRB2ALDH1A1MEN1GAA
SCHEMBL23591373 0.78 GABRA1 (0.66) GABRA1GABRB2CNR2CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118948982-A Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis 尤尼根公司 2024-11-15 CN disclosed
CN-115515614-B Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis 尤尼根公司 2024-07-23 CN disclosed
CN-115515614-A Compositions comprising extracts of alpinia and other plants for improving joint health and treating arthritis 尤尼根公司 2022-12-23 CN disclosed