Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.74 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.74 |
| ▸ | CNR2 | P34972 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | CNR1 | P21554 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | PPARD | Q03181 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31341380 | 0.87 | GABRA1 (0.71) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL18838054 | 0.87 | GABRA1 (0.71) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL27405804 | 0.86 | GABRA1 (0.74) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL23728222 | 0.85 | GABRA1 (0.65) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL525761 | 0.85 | GABRA1 (1.00) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL4621763 | 0.84 | ALDH1A1 (0.71) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL22296495 | 0.84 | GABRA1 (1.00) | GABRA1GABRB2CNR2CNR1MEN1 | |
| SCHEMBL30140765 | 0.83 | GABRA1 (0.67) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL18838069 | 0.83 | GABRA1 (0.67) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL31341318 | 0.83 | GABRA1 (0.67) | GABRA1GABRB2CNR2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083739-B2 | Mito-magnolol compounds and methods of synthesis and use thereof | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200222433-A1 | MITO-MAGNOLOL COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2020-07-16 | — | — | US | disclosed |
| EP-2423181-A1 | Multitarget substituted biphenyl diol derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2012-02-29 | — | — | EP | disclosed |
| EP-2423181-A1 | Multitarget substituted biphenyl diol derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2012-02-29 | — | — | EP | disclosed |
| WO-2012013691-A1 | MULTITARGET SUBSTITUTED BIPHENYL DIOL DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012013691-A1 | MULTITARGET SUBSTITUTED BIPHENYL DIOL DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222433-A1 | MITO-MAGNOLOL COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | CYP11B1, MFN2, CYP11B2 | GABRA1 2692/4885GABRB2 1803/4885CNR2 2796/4885 |
| US-11083739-B2 | Mito-magnolol compounds and methods of synthesis and use thereof | CYP11B1, MFN2, CYP11B2 | GABRA1 2692/4885GABRB2 1803/4885CNR2 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.