Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | NAMPT | P43490 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926283 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1NAMPTKMT2AACKR3 | |
| Hydrochloric Acid SCHEMBL19926156 | 0.99 | OPRM1 (0.48) | OPRM1OPRD1NAMPTKMT2AACKR3 | |
| SCHEMBL30142531 | 0.88 | OPRM1 (0.60) | OPRM1OPRD1NAMPTKMT2AALDH1A1 | |
| SCHEMBL19925981 | 0.88 | OPRM1 (0.60) | OPRM1OPRD1NAMPTKMT2AALDH1A1 | |
| SCHEMBL30142486 | 0.87 | ACKR3 (0.45) | OPRM1OPRD1NAMPTACKR3ALDH1A1 | |
| SCHEMBL19926246 | 0.87 | ACKR3 (0.45) | OPRM1OPRD1NAMPTACKR3CHRNB2 | |
| SCHEMBL19925902 | 0.87 | ACKR3 (0.45) | OPRM1OPRD1NAMPTACKR3ALDH1A1 | |
| SCHEMBL30142519 | 0.87 | ACKR3 (0.45) | OPRM1OPRD1NAMPTACKR3CHRNB2 | |
| SCHEMBL30142490 | 0.87 | ACKR3 (0.45) | OPRM1OPRD1NAMPTACKR3ALDH1A1 | |
| SCHEMBL21116504 | 0.86 | ACKR3 (0.56) | NAMPTACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843379-B | Substituted ureas and methods of making and using the same | 梅比斯发现公司 | 2022-12-30 | — | — | CN | disclosed |