Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25864715 | 1.00 | THRB (0.42) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL874663 | 0.97 | TSHR (0.43) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL627684 | 0.97 | TSHR (0.43) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL4482068 | 0.91 | HTT (0.44) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL273877 | 0.91 | ALDH1A1 (0.47) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL17580775 | 0.91 | HTT (0.48) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL12680272 | 0.91 | ALDH1A1 (0.47) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL11970056 | 0.91 | ALDH1A1 (0.47) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL11970063 | 0.91 | ALDH1A1 (0.47) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL10057435 | 0.91 | ALDH1A1 (0.47) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411458-A1 | TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING | Roche Sequencing Solutions, Inc. | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411458-A1 | TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING | PHAX, DNTT, NSUN3 | THRB 2574/4885HTT 505/4885MEN1 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.