Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.52 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL30145281 | 0.93 | TACR1 (0.47) | TACR1GRM5RIPK1ALDH1A1 | |
| SCHEMBL6064290 | 0.86 | TACR1 (0.54) | TACR1GRM5RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL6064294 | 0.86 | TACR1 (0.54) | TACR1GRM5RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL5218238 | 0.85 | TACR1 (0.53) | TACR1GRM5RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL6550098 | 0.85 | TACR1 (0.53) | TACR1GRM5RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL5811883 | 0.76 | TACR1 (0.43) | TACR1GRM5RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL5255105 | 0.74 | TACR1 (0.44) | TACR1HSP90AA1HSP90AB1 | |
| SCHEMBL31718391 | 0.72 | TACR1 (0.78) | TACR1 | |
| SCHEMBL19442742 | 0.72 | TACR1 (0.78) | TACR1 | |
| SCHEMBL13451348 | 0.72 | TACR1 (0.78) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106421793-B | Compositions and methods for treating centrally mediated nausea and vomiting | 赫尔森保健股份公司 | 2023-06-16 | — | — | CN | disclosed |
| US-20220409599-A1 | USE AND COMPOSITION FOR PROTECTION AGAINST ORGANOPHOSPHORUS POISONING | CLARENCE SMITH KATHLEEN E (US) | 2022-12-29 | — | — | US | disclosed |