Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | THRA | P10827 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30514209 | 0.83 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL4866699 | 0.83 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL4865203 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL4005306 | 0.80 | ALDH1A1 (0.71) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL4858016 | 0.80 | ALDH1A1 (0.71) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL3066269 | 0.80 | ALDH1A1 (0.78) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL19305874 | 0.79 | ALDH1A1 (0.60) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL10800952 | 0.78 | MEN1 (0.74) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL6318160 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL30567324 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1KMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204207-A1 | Compounds and Methods for Treating Dyslipidemia | CHEN XINCHAO | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204207-A1 | Compounds and Methods for Treating Dyslipidemia | APOB, LIPC, PCSK9 | ALDH1A1 1541/4885LMNA 296/4885MEN1 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.