Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 4/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24448445 | 1.00 | EIF4A3 (0.47) | EIF4A3CNR1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL1144892 | 0.85 | EIF4A3 (0.63) | EIF4A3CNR1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL29655546 | 0.85 | EIF4A3 (0.63) | EIF4A3CNR1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL30310432 | 0.83 | RHEB (0.55) | EIF4A3KDM4ELMNAHPGDTSHR | |
| SCHEMBL20505359 | 0.83 | FLT3 (0.45) | EIF4A3KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL21624015 | 0.83 | MAP2K1 (0.49) | EIF4A3KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL29063125 | 0.83 | GRIN1 (0.50) | EIF4A3KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL16234661 | 0.82 | EIF4A3 (0.51) | EIF4A3CNR1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL30067362 | 0.82 | EIF4A3 (0.47) | EIF4A3CNR1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL20504845 | 0.79 | RHEB (0.45) | KDM4EHPGDTDP1RHEBMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |