Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | RHEB | Q15382 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144892 | 1.00 | EIF4A3 (0.63) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL30536689 | 0.86 | EIF4A3 (0.49) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL24448445 | 0.85 | EIF4A3 (0.47) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL30147573 | 0.85 | EIF4A3 (0.47) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL16234661 | 0.85 | EIF4A3 (0.51) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL30067362 | 0.85 | EIF4A3 (0.47) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL15515831 | 0.84 | GRIN1 (0.70) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL21624049 | 0.84 | KDM4E (0.51) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL20505503 | 0.84 | EIF4A3 (0.54) | EIF4A3KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL29974385 | 0.84 | GRIN1 (0.70) | EIF4A3KDM4EHSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587433-A1 | 3-(1H-INDOLE-2-CARBONYL)-6,6-DIMETHYL-N-((S)-1-OXO-3-((S)-2-OXOPYRROLIDIN-3-YL)P ROPAN-2-YL)-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE DERIVATIVES AS MPRO INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | Takeda Pharmaceutical Company Limited (JP) | 2025-07-23 | — | — | EP | disclosed |
| WO-2025101881-A1 | HETEROATOM CONTAINING PEPTIDOMIMETICS TARGETING VIRAL PROTEASES | EMORY UNIVERSITY (US) | 2025-05-15 | — | — | WO | disclosed |
| CN-119638737-A | Macrocyclic compounds and their use in medicine | 广东东阳光药业股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2025036439-A1 | MULTICYCLIC COMPOUNDS AND THEIR USE AS PI3K ALPHA INHIBITORS | LAEKNA PHARMACEUTICAL NINGBO CO., LTD. (CN) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024059087-A1 | 3-(1H-INDOLE-2-CARBONYL)-6,6-DIMETHYL-N-((S)-1-OXO-3-((S)-2-OXOPYRROLIDIN-3-YL)P ROPAN-2-YL)-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE DERIVATIVES AS MPRO INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-03-21 | — | — | WO | disclosed |
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-116813697-A | Halogenated benzene ring-spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116621917-A | Difluoro indole-spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116348477-A | Functionalized peptides as antiviral agents | 英安塔制药有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116178367-A | Application of benzoheterocycle compounds in treatment or prevention of hepatitis B | 中以海德人工智能药物研发股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2023086350-A1 | ALKYNE-CONTAINING ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-4161916-A1 | SUBSTITUTED ISOQUINOLINYLMETHYL AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-04-12 | — | — | EP | disclosed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |
| US-20230040909-A1 | INDOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT INC (US) | 2023-02-09 | — | — | US | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-114671795-B | Indole compound, preparation method and application thereof in aldehyde ketone detection | 中国环境科学研究院 | 2022-08-19 | — | — | CN | disclosed |
| EP-4034103-A1 | INDOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| CN-114524821-A | Novel spiropyrrolidine derived antiviral drugs | 英安塔制药有限公司 | 2022-05-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230040909-A1 | INDOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | IDO1, IDO2, INMT | EIF4A3 3180/4885KDM4E 1303/4885HSD17B10 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.