Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655546 | 0.85 | EIF4A3 (0.63) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL1144892 | 0.85 | EIF4A3 (0.63) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL16234661 | 0.82 | EIF4A3 (0.51) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL24448445 | 0.82 | EIF4A3 (0.47) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL30147573 | 0.82 | EIF4A3 (0.47) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL4276853 | 0.78 | ULK1 (0.49) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL29897794 | 0.78 | ULK1 (0.49) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL18183345 | 0.78 | CNR1 (0.48) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL25474874 | 0.77 | EIF4A3 (0.47) | EIF4A3CNR1KDM4ELMNAHPGD | |
| SCHEMBL30536689 | 0.76 | EIF4A3 (0.49) | EIF4A3CNR1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638737-A | Macrocyclic compounds and their use in medicine | 广东东阳光药业股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2022240541-A1 | NOVEL MACROCYCLIC SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |