Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712936 | 1.00 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL606570 | 1.00 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL606571 | 1.00 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL23972979 | 0.89 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8866869 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8868101 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8866876 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8866872 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL276569 | 0.85 | LMNA (0.73) | LMNAMAPK1KMT2ASRCBLM | |
| SCHEMBL5064611 | 0.82 | PARP1 (0.50) | MEN1KMT2AACP3GLSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417923-A | Nitrilase mutant and application thereof | 浙江工业大学 | 2024-01-19 | — | — | CN | disclosed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |