Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866876 | 1.00 | LMNA (0.50) | LMNAMAPK1MEN1KMT2ATRPM8 | |
| SCHEMBL8866872 | 1.00 | LMNA (0.50) | LMNAMAPK1MEN1KMT2ATRPM8 | |
| SCHEMBL8868101 | 1.00 | LMNA (0.50) | LMNAMAPK1MEN1KMT2ATRPM8 | |
| SCHEMBL30147772 | 0.87 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL606571 | 0.87 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL1712936 | 0.87 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL606570 | 0.87 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| Mandelic Acid SCHEMBL28826203 | 0.84 | LMNA (0.72) | LMNAMAPK1HIF1AKDM4EALDH1A1 | |
| Mandelic Acid SCHEMBL28053312 | 0.84 | LMNA (0.72) | LMNAMAPK1HIF1AKDM4EALDH1A1 | |
| SCHEMBL148751 | 0.78 | ADRB2 (0.54) | LMNAACP3ALDH1A1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663360-A | REACTING 3,4-DIMETHOXYAMPHETAMINE WITH 3-CHLOROMANDELIC ACID | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 1997-09-02 | — | — | US | claimed |
| US-5663360-A | REACTING 3,4-DIMETHOXYAMPHETAMINE WITH 3-CHLOROMANDELIC ACID | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 1997-09-02 | — | — | US | disclosed |