Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712936 | 1.00 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL30147772 | 1.00 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL606570 | 1.00 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL23972979 | 0.89 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8866869 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8868101 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8866876 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL8866872 | 0.87 | LMNA (0.50) | LMNAMAPK1MEN1KMT2AACP3 | |
| SCHEMBL276569 | 0.85 | LMNA (0.73) | LMNAMAPK1KMT2ASRCBLM | |
| SCHEMBL5064611 | 0.82 | PARP1 (0.50) | MEN1KMT2AACP3GLSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-113355367-B | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-113355299-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113355299-A | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | claimed |
| CN-113355367-A | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | claimed |
| CN-109467502-B | Method for splitting mandelic acid compound enantiomer | 湖南科技大学 | 2021-07-30 | — | — | CN | claimed |
| CN-108410831-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-07-27 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| CN-108410831-A | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2018-08-17 | — | — | CN | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| US-20070270487-A1 | Novel process and intermediates 085 | ASTRAZENECA AB (SE) | 2007-11-22 | — | — | US | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| US-20040242693-A1 | Optically active mandelic acid and its derivative, and method for crystallization thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-12-02 | — | — | US | claimed |
| EP-1449821-A1 | OPTICALLY ACTIVE MANDELIC ACID AND ITS DERIVATIVE, AND METHOD FOR CRYSTALLIZATION THEREOF | Nippon Shokubai Co., Ltd. (JP) | 2004-08-25 | — | — | EP | claimed |
| US-5663360-A | REACTING 3,4-DIMETHOXYAMPHETAMINE WITH 3-CHLOROMANDELIC ACID | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 1997-09-02 | — | — | US | claimed |
| US-5198586-A | Process for the preparation of phenylethanolaminotetralins | SANOFI (FR) | 1993-03-30 | — | — | US | claimed |
| EP-0303545-B1 | PROCESS FOR THE PREPARATION OF PHENYLETHANOLAMINOTETRALINES | ELF SANOFI (FR) | 1992-06-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | LMNA 4734/4885MAPK1 1427/4885MEN1 4428/4885 |
| US-20070270487-A1 | Novel process and intermediates 085 | CYP3A5, AGPAT5, CYP4F8 | LMNA 3669/4885MAPK1 1719/4885MEN1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.