Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetraphenylporphyrin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYCS | P99999 | 3/20 | 0.61 |
| ▸ | TERT | O14746 | 5/20 | 0.60 |
| ▸ | TOP1 | P11387 | 4/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylporphyrin SCHEMBL30148172 | 1.00 | CYCS (0.61) | CYCSTERTTOP1STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL1465445 | 0.98 | TOP1 (0.60) | CYCSTERTTOP1STAT3STAT1 | |
| Tetraphenylporphyrin SCHEMBL29995931 | 0.96 | CYCS (0.61) | CYCSTERTTOP1STAT3STAT1 | |
| SCHEMBL29405816 | 0.96 | TOP1 (0.62) | CYCSTERTTOP1STAT3STAT1 | |
| Tetraphenylporphyrin SCHEMBL30006197 | 0.96 | CYCS (0.65) | CYCSTERTTOP1STAT3STAT1 | |
| Tetraphenylporphyrin SCHEMBL578886 | 0.96 | CYCS (0.65) | CYCSTERTTOP1STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL30909509 | 0.94 | TOP1 (0.60) | CYCSTERTTOP1STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL483551 | 0.94 | TOP1 (0.60) | CYCSTERTTOP1STAT3STAT1 | |
| SCHEMBL18510098 | 0.94 | CYCS (0.63) | CYCSTERTTOP1STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL483749 | 0.94 | TOP1 (0.60) | CYCSTERTTOP1STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11796543-B2 | Colorimetric system for detection of COVID-19 using salivary metabolites | Farin Behbood Tashkhis Company (IR) | 2023-10-24 | — | — | US | disclosed |
| WO-2023148541-A1 | COLORIMETRIC SYSTEM FOR DETECTION OF COVID-19 USING SALIVARY METABOLITES | BAGHERI HASAN (IR) | 2023-08-10 | — | — | WO | disclosed |
| US-20220334114-A1 | COLORIMETRIC SYSTEM FOR DETECTION OF COVID-19 USING SALIVARY METABOLITES | Bagheri, Hasan (IR) | 2022-10-20 | — | — | US | disclosed |