Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | CYCS | P99999 | 3/20 | 0.58 |
| ▸ | TERT | O14746 | 4/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylporphyrin SCHEMBL30148173 | 0.98 | CYCS (0.61) | TOP1STAT3STAT1CYCSTERT | |
| Tetraphenylporphyrin SCHEMBL30148172 | 0.98 | CYCS (0.61) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL29405816 | 0.98 | TOP1 (0.62) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL30306704 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL29440936 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL29872728 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483551 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483749 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL30909509 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483505 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109755504-A | Application containing ferriporphyrin/carbon/carbon nano tube compound anode material preparation method and its in lithium-sulphur cell positive electrode | 温州大学 | 2019-05-14 | — | — | CN | claimed |
| CN-107417535-B | A kind of one-pot synthesis method of highly selective (E)-beta-nitrostyrene derivative | 沅江华龙催化科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-107098811-B | (E)-beta-nitrostyrene synthetic method | 沅江华龙催化科技有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-106995373-B | Using ammonium iodide as nitro source one-pot synthesis α, β-unsaturation nitroolefin derivative method | 沅江华龙催化科技有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-106995372-B | A method of (E)-beta-nitrostyrene derivative is catalyzed and synthesized based on tetaraary porphyrin iron | 沅江华龙催化科技有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-106290631-B | A kind of method of pigment array sensing technology Fast Evaluation magma Quality of Liquors | 江苏今世缘酒业股份有限公司 | 2018-11-27 | — | — | CN | claimed |
| CN-107417535-A | A kind of One-step Synthesis method of high selectivity (E) β nitrostyrene derivatives | 沅江华龙催化科技有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-107098811-A | (E) synthetic method of β nitrostyrolenes | 沅江华龙催化科技有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107032939-A | The synthetic method of α, β unsaturation nitroolefin derivative | 沅江华龙催化科技有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-106995372-A | One kind is catalyzed and synthesized based on tetaraary porphyrin iron（E）The method of β nitrostyrene derivatives | 沅江华龙催化科技有限公司 | 2017-08-01 | — | — | CN | claimed |
| US-20040041082-A1 | Molecular sensing array | BANK OF THE WEST | 2004-03-04 | — | — | US | claimed |
| JP-2002510305-A | — | — | 2002-04-02 | — | — | JP | claimed |
| EP-1062221-A4 | PROCESS FOR MAKING GLYPHOSATE BY OXIDIZING N-SUBSTITUTED GLYPHOSATES | MONSANTO TECHNOLOGY LLC (US) | 2001-10-17 | — | — | EP | claimed |
| US-20010018536-A1 | Process for the preparation of n- (phosphonomethyl) glycine by oxidizing n-substituted n-(phosphonomethyl) glycine | MONSANTO TECHNOLOGY LLC | 2001-08-30 | — | — | US | claimed |
| US-6245707-B1 | HEAT TREATED ELECTROCATALYST MIXTURE OF TWO DIFFERENT CHELATE COMPOUNDS COMPRISING NITROGENOUS LIGAND-CHELATED TRANSITION METALS OTHER THAN PLATINUM OR PALLADIUM; IMPROVED OXYGEN REDUCTION AT A FUEL CELL CATHODE AFTER METHANOL CROSSOVER | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2001-06-12 | — | — | US | claimed |
| US-6232494-B1 | CATALYTIC OXIDATION | MONSANTO COMPANY | 2001-05-15 | — | — | US | claimed |
| EP-1062221-A1 | PROCESS FOR MAKING GLYPHOSATE BY OXIDIZING N-SUBSTITUTED GLYPHOSATES | MONSANTO COMPANY (US) | 2000-12-27 | — | — | EP | claimed |
| US-6005140-A | USING A NOBLE METAL OXIDATION CATALYST | MONSANTO COMPANY (US) | 1999-12-21 | — | — | US | claimed |
| WO-1999041260-A1 | PROCESS FOR MAKING GLYPHOSATE BY OXIDIZING N-SUBSTITUTED GLYPHOSATES | MONSANTO COMPANY (US) | 1999-08-19 | — | — | WO | claimed |
| US-5444134-A | Using a coordination catalyst | IDEMITSU KOSAN CO., LTD. (JP) | 1995-08-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018536-A1 | Process for the preparation of n- (phosphonomethyl) glycine by oxidizing n-substituted n-(phosphonomethyl) glycine | GNMT, GRHPR, GLRA3 | TOP1 3870/4885STAT3 2155/4885STAT1 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.