Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.44 |
| ▸ | CLK2 | P49760 | 2/20 | 0.44 |
| ▸ | CDK7 | P50613 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148820 | 0.85 | EZH2 (0.46) | FLT3EZH2CDK1CSNK1ECSNK1D | |
| SCHEMBL30148823 | 0.84 | CTSL (0.45) | FLT3EZH2CDK1CTSL | |
| SCHEMBL30148797 | 0.83 | TDP1 (0.49) | FLT3EZH2CDK1CTSL | |
| SCHEMBL30148805 | 0.83 | FLT3 (0.50) | FLT3PDGFRAEZH2 | |
| SCHEMBL30148813 | 0.80 | EZH2 (0.43) | FLT3EZH2EHMT2CDK1CDK5 | |
| SCHEMBL30148787 | 0.76 | YTHDC1 (0.59) | FLT3 | |
| SCHEMBL30148817 | 0.75 | ADORA3 (0.44) | CDK1CTSL | |
| SCHEMBL30148777 | 0.75 | TDP1 (0.44) | FLT3EZH2CDK1CTSL | |
| SCHEMBL15243311 | 0.75 | CSNK1E (0.67) | FLT3CSNK1ECDK12CCNKCSNK1D | |
| SCHEMBL30148811 | 0.75 | TDP1 (0.48) | FLT3CDK1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903289-B | Purine-aminomethyl-pyridone derivative, preparation method and application thereof | 四川大学 | 2023-02-03 | — | — | CN | disclosed |