Diphenylamine

Diphenylamine

SCHEMBL301493

c1ccc(Nc2ccccc2)cc1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 1.00
ALDH1A1 P00352 8/20 0.92
TDP1 Q9NUW8 8/20 0.92
TSHR P16473 5/20 0.92
ALOX12 P18054 3/20 0.92
L3MBTL1 Q9Y468 3/20 0.92
ALOX15 P16050 2/20 0.92
PTGS2 P35354 2/20 0.92
PTGS1 P23219 1/20 0.92
SLC6A2 P23975 1/20 0.92
MAPK1 P28482 1/20 0.92
HTR2B P41595 1/20 0.92
MAPT P10636 6/20 0.75
MEN1 O00255 5/20 0.75
KMT2A Q03164 5/20 0.75
AR P10275 1/20 0.75
CYP3A4 P08684 6/20 0.67
CYP1A2 P05177 3/20 0.67
CYP2C9 P11712 3/20 0.67
CYP2C19 P33261 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL229 1.00 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL3003404 1.00 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL6828443 1.00 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL1619083 1.00 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL23295988 0.96 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL634477 0.96 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL192934 0.96 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL3357779 0.96 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
SCHEMBL9480038 0.96 ALDH1A1 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL9362761 0.96 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107445886-A A kind of preparation method of the phenyl carbazole of 3 bromine of high-purity 9 北京八亿时空液晶科技股份有限公司 2017-12-08 CN claimed
EP-1735412-B1 KETONE DIARYLAMINE CONDENSATES CHEMTURA CORP (US) 2012-03-14 EP claimed
CN-111088183-B Marine vibrio and application thereof in preparation of iota-carrageenase with thermal stability 青岛大学 2021-07-13 CN disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
CN-109735520-B Iota-carrageenase with thermal stability and application thereof 青岛大学 2020-06-05 CN disclosed
CN-109762799-B Kappa-carrageenase and application thereof 青岛大学 2020-06-05 CN disclosed
CN-111088183-A Marine vibrio and application thereof in preparation of iota-carrageenase with thermal stability 青岛大学 2020-05-01 CN disclosed
CN-111004755-A Citrobacter T26 for specifically degrading hyaluronic acid, hyaluronidase HylC produced by Citrobacter T26 and application of hyaluronidase HylC 中国海洋大学 2020-04-14 CN disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed