Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.92 |
| ▸ | TSHR | P16473 | 5/20 | 0.92 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.92 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.92 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.92 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.92 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.92 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.92 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.92 |
| ▸ | HTR2B | P41595 | 1/20 | 0.92 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | AR | P10275 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL229 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL3003404 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL301493 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL1619083 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL23295988 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL634477 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL192934 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL3357779 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL9480038 | 0.96 | ALDH1A1 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL9362761 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385919-A1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USES | Cambridge Display Technology Limited (GB) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002092724-A1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2002-11-21 | — | — | WO | disclosed |