Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.92 |
| ▸ | TSHR | P16473 | 5/20 | 0.92 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.92 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.92 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.92 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.92 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.92 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.92 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.92 |
| ▸ | HTR2B | P41595 | 1/20 | 0.92 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | AR | P10275 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL229 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL6828443 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL1619083 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL301493 | 1.00 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL23295988 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL233665 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL8602771 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL7896372 | 0.96 | ALDH1A1 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL1555489 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL11684039 | 0.96 | HSD17B10 (0.92) | HSD17B10ALDH1A1TDP1TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113981475-A | Electrochemical method for preparing N-alkyl sulfoxide imide | 常州工学院 | 2022-01-28 | — | — | CN | disclosed |
| CN-107018662-B | 6, 7-dihydropyrazolo [1,5-a ] pyrazin-4 (5H) -one compounds and their use as negative allosteric modulators of MGLUR2 receptors | 詹森药业有限公司 | 2020-01-07 | — | — | CN | disclosed |
| US-20100193979-A1 | Advanced Thermoplastics for Orthodontics | UNIVERSITY OF CONNECTICUT | 2010-08-05 | — | — | US | disclosed |
| WO-2008088826-A2 | TRANSLUCENT, ISOTROPIC ENDODONTIC POST | UNIVERSITY OF CONNECTICUT (US) | 2008-07-24 | — | — | WO | disclosed |
| US-20080171306-A1 | Translucent, isotropic endodontic post | CONNECTICUT, UNIVERSITY OF | 2008-07-17 | — | — | US | disclosed |
| US-20070190478-A1 | Advanced thermoplastics for orthodontics | GOLDBERG ARTIE J | 2007-08-16 | — | — | US | disclosed |
| US-7186115-B2 | Advanced thermoplastics for orthodontics | UNIVERSITY OF CONNECTICUT (US) | 2007-03-06 | — | — | US | disclosed |
| EP-1539020-A4 | ADVANCED THERMOPLASTICS FOR ORTHODONTICS | UNIV CONNECTICUT (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6933068-B2 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) | 2005-08-23 | — | — | US | disclosed |
| EP-1539020-A1 | ADVANCED THERMOPLASTICS FOR ORTHODONTICS | The University of Connecticut (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040013994-A1 | Advanced thermoplastics for orthodontics | UNIVERSITY OF CONNECTICUT | 2004-01-22 | — | — | US | disclosed |
| WO-2004004592-A1 | ADVANCED THERMOPLASTICS FOR ORTHODONTICS | UNIVERSITY OF CONNECTICUT (US) | 2004-01-15 | — | — | WO | disclosed |
| US-20020172850-A1 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-0773249-B1 | Polyphenylene co-polymers | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6416834-B1 | Composition for improving adhesion of elastomers to polymer compositions | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-07-09 | — | — | US | disclosed |
| US-5886130-A | THE CO-POLYMERS ARE USEFUL AS MOLDING RESINS, AND COMPOSITE MATRIX RESINS, AND WHERE AR IS HETEROARYLENE AS ION EXCHANGE RESINS. | MAXDEM INCORPORATED (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0773249-A1 | Polyphenylene co-polymers | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0387194-B1 | N-substituted aminoalkane-diphosphonic acids | CIBA GEIGY AG (CH) | 1995-01-18 | — | — | EP | disclosed |
| US-5036058-A | Regulates calcium metabolism | CIBA-GEIGY CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0387194-A1 | N-substituted aminoalkane-diphosphonic acids | CIBA-GEIGY AG (CH) | 1990-09-12 | — | — | EP | disclosed |