Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662936 | 0.88 | ESR2 (0.53) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28133054 | 0.88 | ESR2 (0.53) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13606454 | 0.81 | ESR2 (0.47) | ESR2CTSAGABRG2GABRB3GABRA5 | |
| SCHEMBL2652196 | 0.80 | ESR2 (0.46) | ESR2CTSAGABRG2GABRB3GABRA5 | |
| SCHEMBL2648336 | 0.80 | ESR2 (0.46) | ESR2CTSAGABRG2GABRB3GABRA5 | |
| SCHEMBL5003746 | 0.77 | GABRG2 (0.56) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3634470 | 0.77 | ACHE (0.43) | CTSA | |
| SCHEMBL1372803 | 0.77 | ALOX5AP (0.52) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28299311 | 0.75 | ESR2 (0.52) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2183512 | 0.75 | ESR2 (0.47) | ESR2GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110337433-B | Compounds and pharmaceutical compositions for modulating SGK activity and methods thereof | 南京奥利墨斯医药科技有限公司 | 2023-02-28 | — | — | CN | disclosed |