SCHEMBL30150752

SCHEMBL30150752

Cc1cccc2cccnc12.[N]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
CCR1 P32246 4/20 0.58
CCR8 P51685 4/20 0.58
KDM4E B2RXH2 4/20 0.58
MAPT P10636 4/20 0.58
CCR5 P51681 3/20 0.58
MMP2 P08253 2/20 0.58
TSHR P16473 2/20 0.58
HSP90AA1 P07900 2/20 0.58
ALOX15 P16050 2/20 0.58
HTT P42858 2/20 0.58
GMNN O75496 1/20 0.58
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2D6 P10635 1/20 0.58
MMP9 P14780 1/20 0.58
NFKB1 P19838 1/20 0.58
MMP8 P22894 1/20 0.58
THPO P40225 1/20 0.58
MTOR P42345 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664407 0.98 CCR1 (0.61) LMNACCR1CCR8KDM4EMAPT
SCHEMBL256942 0.98 CCR1 (0.61) LMNACCR1CCR8KDM4EMAPT
Ammonia Solution, Strong SCHEMBL28014320 0.95 LMNA (0.59) LMNACCR1CCR8KDM4EMAPT
Bicarbonate SCHEMBL9198375 0.88 PARP1 (0.53) LMNACCR1CCR8KDM4EMAPT
SCHEMBL7745077 0.86 LMNA (0.55) LMNACCR1CCR8KDM4EMAPT
Quinoline SCHEMBL28253161 0.86 ALDH1A1 (0.63) LMNACCR1CCR8KDM4EMAPT
SCHEMBL27975277 0.86 SLC40A1 (0.54) LMNACCR1CCR8KDM4EMAPT
Isothiocyanate SCHEMBL27404432 0.86 LMNA (0.50) LMNACCR1CCR8KDM4EMAPT
SCHEMBL10525606 0.86 LMNA (0.50) LMNACCR1CCR8KDM4EMAPT
SCHEMBL9400641 0.85 KDR (0.50) LMNACCR1CCR8KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776412-B Synthesis method of N oxide 陕西大生制药科技有限公司 2022-12-13 CN disclosed