Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 3/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054960 | 0.90 | KIF11 (0.45) | NPC1RAB9AHTTALDH1A1MAPT | |
| SCHEMBL24054781 | 0.78 | MAPT (0.48) | NPC1RAB9AHTTALDH1A1MAPT | |
| SCHEMBL22042759 | 0.76 | MAPT (0.49) | NPC1RAB9AMAPTKIF11MEN1 | |
| SCHEMBL30151244 | 0.76 | MAPT (0.49) | NPC1RAB9AMAPTKIF11MEN1 | |
| SCHEMBL19995446 | 0.76 | KMT2A (0.46) | NPC1RAB9AHTTMAPTMEN1 | |
| SCHEMBL30151263 | 0.73 | MAPT (0.49) | NPC1RAB9AHTTALDH1A1MAPT | |
| SCHEMBL25511346 | 0.72 | LATS1 (0.54) | NPC1RAB9AHTTALDH1A1MAPT | |
| SCHEMBL20011841 | 0.72 | MEN1 (0.49) | NPC1RAB9AHTTMAPTMEN1 | |
| SCHEMBL30151272 | 0.72 | KIF11 (0.45) | NPC1RAB9AHTTMAPTKIF11 | |
| SCHEMBL30151306 | 0.70 | KIF11 (0.40) | NPC1RAB9AHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504704-A | Fluoropyrimidine compounds fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115551840-B | Fluoropyrimidine compounds fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115551840-A | Fluorine-containing pyrimidine compound and fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2022-12-30 | — | — | CN | disclosed |