Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151252 | 0.81 | CYP19A1 (0.51) | PSDALDH1A1RAB9ANPC1PDE5A | |
| SCHEMBL24054960 | 0.75 | KIF11 (0.45) | KIF11ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL30151310 | 0.74 | CCR1 (0.53) | ALDH1A1RAB9ANPC1HTTMAPK1 | |
| SCHEMBL12763840 | 0.72 | KIF11 (0.42) | KIF11PSDRAB9AMAPTNPC1 | |
| SCHEMBL5809565 | 0.71 | KDM4E (0.50) | ALDH1A1MAPTMAPK1KDM4EHSD17B10 | |
| SCHEMBL30151284 | 0.70 | NPC1 (0.41) | KIF11ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL21385116 | 0.68 | MAPK1 (0.50) | PSDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL24331214 | 0.67 | BACE1 (0.34) | ALDH1A1RAB9ANPC1PIK3CDKDM4E | |
| SCHEMBL28620070 | 0.67 | LMNA (0.58) | KIF11RAB9AMAPTNPC1PIK3CD | |
| SCHEMBL24054781 | 0.66 | MAPT (0.48) | KIF11ALDH1A1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551840-A | Fluorine-containing pyrimidine compound and fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2022-12-30 | — | — | CN | disclosed |