Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054772 | 0.82 | MAPT (0.50) | MAPTNPSR1SMN1; SMN2HTTXBP1 | |
| SCHEMBL24054960 | 0.79 | KIF11 (0.45) | MAPTSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL25511346 | 0.76 | LATS1 (0.54) | MAPTSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL30151284 | 0.73 | NPC1 (0.41) | MAPTHTTALDH1A1LMNAMEN1 | |
| SCHEMBL24054781 | 0.71 | MAPT (0.48) | MAPTNPSR1SMN1; SMN2HTTXBP1 | |
| SCHEMBL30151224 | 0.71 | MAPT (0.48) | MAPTNPSR1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4071345 | 0.70 | NPC1 (0.51) | SMN1; SMN2ALDH1A1LMNATSHRHPGD | |
| SCHEMBL19743183 | 0.66 | NPC1 (0.63) | MAPTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL257957 | 0.65 | DDAH1 (0.70) | MAPTNPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4063890 | 0.64 | DHPS (0.47) | NPSR1SMN1; SMN2HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504704-A | Fluoropyrimidine compounds fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115551840-B | Fluoropyrimidine compounds fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115551840-A | Fluorine-containing pyrimidine compound and fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2022-12-30 | — | — | CN | disclosed |