Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESRRG | P62508 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969084 | 1.00 | NPC1 (0.55) | NPC1RAB9ATSHRHPGDHTT | |
| SCHEMBL1197766 | 0.88 | ALDH1A1 (0.57) | FADS1MEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL28747395 | 0.83 | LMNA (0.61) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL18146698 | 0.83 | FADS1 (0.56) | NPC1RAB9ATSHRHPGDHTT | |
| SCHEMBL25395905 | 0.81 | HDAC1 (0.56) | NPC1RAB9AFADS1MEN1KMT2A | |
| SCHEMBL677811 | 0.80 | SNCA (0.67) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18941291 | 0.80 | NPC1 (0.73) | NPC1RAB9ATSHRHPGDMEN1 | |
| SCHEMBL31424183 | 0.79 | PTGS1 (0.68) | NPC1RAB9ATSHRHPGDHTT | |
| SCHEMBL5221775 | 0.79 | PTGS1 (0.68) | NPC1RAB9ATSHRHPGDHTT | |
| SCHEMBL1353546 | 0.79 | NPC1 (0.71) | NPC1RAB9ATSHRHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |