Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.59 |
| ▸ | F13A1 | P00488 | 3/20 | 0.47 |
| ▸ | TGM1 | P22735 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 2/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968501 | 1.00 | TGM2 (0.59) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL3547407 | 0.83 | KDR (0.69) | TGM2LMNATEKTMPRSS4KDR | |
| SCHEMBL31596069 | 0.83 | TGM2 (0.58) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL4687828 | 0.80 | KDR (0.51) | LMNATMPRSS4KDRHSD17B10 | |
| SCHEMBL3549419 | 0.80 | TGM2 (0.58) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL28295696 | 0.80 | TGM2 (0.56) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL30230722 | 0.80 | TGM2 (0.54) | TGM2LMNABTK | |
| SCHEMBL21924973 | 0.80 | TGM2 (0.54) | TGM2 | |
| SCHEMBL30152202 | 0.79 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL24969561 | 0.79 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |