Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14452374 | 0.87 | BRD4 (0.50) | LMNAMAPTSMN1; SMN2NR3C1MEN1 | |
| SCHEMBL15957207 | 0.86 | LMNA (0.49) | LMNAHPGDHSD17B10MAPTCYP19A1 | |
| SCHEMBL5673172 | 0.83 | KDM4E (0.57) | LMNAHPGDHSD17B10CYP19A1SMN1; SMN2 | |
| SCHEMBL8752512 | 0.81 | METAP2 (0.64) | LMNAHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL5310588 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL5309543 | 0.79 | MIF (0.47) | LMNAHPGDHSD17B10CYP19A1NR3C1 | |
| SCHEMBL5674748 | 0.78 | HSD17B10 (0.51) | LMNAHPGDHSD17B10MAPTCYP19A1 | |
| SCHEMBL2738019 | 0.78 | KDM4E (0.56) | HPGDHSD17B10MAPTSMN1; SMN2ALDH1A1 | |
| Lithium SCHEMBL31041218 | 0.78 | HPGD (0.68) | LMNAHPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL16887435 | 0.78 | MAPK1 (0.51) | LMNAHPGDHSD17B10CYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4850702-B2 | — | — | 2012-01-11 | — | — | JP | claimed |