Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 6/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818855 | 1.00 | VSIR (0.36) | VSIRS1PR1S1PR3CD274PDCD1 | |
| SCHEMBL24818800 | 0.94 | VSIR (0.38) | VSIRCD274PDCD1PDCD1LG2 | |
| SCHEMBL30153011 | 0.94 | VSIR (0.38) | VSIRCD274PDCD1PDCD1LG2 | |
| SCHEMBL30152669 | 0.91 | P2RY14 (0.39) | CD274PDCD1PDCD1LG2MAPTSMN1; SMN2 | |
| SCHEMBL24820539 | 0.91 | P2RY14 (0.39) | CD274PDCD1PDCD1LG2MAPTSMN1; SMN2 | |
| SCHEMBL24819949 | 0.91 | OPRK1 (0.31) | S1PR1S1PR3CD274PDCD1LG2HCRTR1 | |
| SCHEMBL30153243 | 0.90 | CBLB (0.34) | CD274PDCD1LG2HCRTR1 | |
| SCHEMBL30152887 | 0.89 | CD274 (0.36) | VSIRCD274PDCD1PDCD1LG2 | |
| SCHEMBL24820542 | 0.89 | CD274 (0.36) | VSIRCD274PDCD1PDCD1LG2 | |
| SCHEMBL24820311 | 0.89 | VSIR (0.37) | VSIRCD274PDCD1PDCD1LG2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163038-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163038-A1 | CBL-B MODULATORS AND USES THEREOF | CBLB, CBL, CBLC | VSIR 1674/4885S1PR1 3402/4885S1PR3 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.