SCHEMBL30153123

SCHEMBL30153123

Cn1cnnc1-c1cc(C#N)ccc1-c1cccc(-c2nc3cc(CO[Si](C)(C)C(C)(C)C)cc(C(F)(F)F)c3o2)c1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 1/20 0.38
▸ CETP P11597 12/20 0.33
▸ CEPT1 Q9Y6K0 4/20 0.33
▸ NSD2 O96028 1/20 0.32
▸ FNTA P49354 3/20 0.31
▸ FNTB P49356 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24818895 1.00 CBLB (0.38) CBLBCETPCEPT1NSD2FNTA
SCHEMBL24819914 0.90 CETP (0.34) CBLBCETP
SCHEMBL30153234 0.90 CETP (0.34) CBLBCETP
SCHEMBL30152890 0.88 CBLB (0.40) CBLBCETPCEPT1NSD2FNTA
SCHEMBL24818896 0.88 CBLB (0.40) CBLBCETPCEPT1NSD2FNTA
SCHEMBL24818812 0.84 CBLB (0.39) CBLBCETPNSD2FNTAFNTB
SCHEMBL30153053 0.84 CBLB (0.39) CBLBCETPNSD2FNTAFNTB
SCHEMBL24818899 0.82 CBLB (0.39) CBLBCETPFNTAFNTB
SCHEMBL30153241 0.82 CBLB (0.39) CBLBCETPFNTAFNTB
SCHEMBL24819909 0.81 CBLB (0.42) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. 2025-05-22 — — US disclosed
EP-4359381-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-05-01 — — EP disclosed
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC CBLB 1/4885CETP 3617/4885CEPT1 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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