Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 4/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.36 |
| ▸ | FNTB | P49356 | 4/20 | 0.36 |
| ▸ | CETP | P11597 | 9/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CBL | P22681 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153241 | 1.00 | CBLB (0.39) | CBLBFNTAFNTBCETPELANE | |
| SCHEMBL24818753 | 0.89 | VSIR (0.34) | CBLBCETPHPGD | |
| SCHEMBL30153254 | 0.89 | CBLB (0.37) | CBLBCETP | |
| SCHEMBL24820501 | 0.89 | CBLB (0.37) | CBLBCETP | |
| SCHEMBL30153053 | 0.88 | CBLB (0.39) | CBLBFNTAFNTBCETPELANE | |
| SCHEMBL24818812 | 0.88 | CBLB (0.39) | CBLBFNTAFNTBCETPELANE | |
| SCHEMBL30152890 | 0.86 | CBLB (0.40) | CBLBFNTAFNTBCETP | |
| SCHEMBL24818896 | 0.86 | CBLB (0.40) | CBLBFNTAFNTBCETP | |
| SCHEMBL24820065 | 0.84 | VSIR (0.34) | CBLBHPGD | |
| SCHEMBL30152989 | 0.84 | VSIR (0.34) | CBLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |