Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012453 | 0.91 | PTGES (0.39) | PPARGCYP3A4CYP3A5PTGES | |
| SCHEMBL3001788 | 0.91 | POLB (0.34) | PPARGPPARA | |
| SCHEMBL3009742 | 0.82 | MAP4K1 (0.37) | PPARGSCN9APTGES | |
| SCHEMBL3006485 | 0.81 | PTGES (0.38) | PPARGPPARASCN9ACYP3A4CYP3A5 | |
| SCHEMBL4228390 | 0.76 | PPARG (0.50) | PPARGPPARAPTGES | |
| SCHEMBL3007687 | 0.73 | PPARG (0.45) | PPARGPPARAPTGES | |
| SCHEMBL4226241 | 0.71 | PPARG (0.44) | PPARGPPARAPTGES | |
| SCHEMBL4227684 | 0.71 | PPARG (0.43) | PPARGPPARASCN9APTGES | |
| SCHEMBL3000984 | 0.70 | MCHR1 (0.36) | PPARA | |
| SCHEMBL333981 | 0.70 | MDM2 (0.44) | PPARGPPARASCN9APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2010-08-05 | — | — | US | disclosed |
| EP-1841736-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077367-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, TPH1 | PPARG 2505/4885PPARA 3519/4885SCN9A 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.