SCHEMBL301556

SCHEMBL301556

Cl[Ti](Cl)(Cl)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.45
TSHR P16473 1/20 0.45
KCNA3 P22001 1/20 0.43
CA4 P22748 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAOA P21397 1/20 0.35
HTR1B P28222 2/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4306110 0.82 LTA4H (0.45) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL302675 0.82 LTA4H (0.45) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL193709 0.75 LTA4H (0.50) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL7593738 0.73 LTA4H (0.47) LTA4HTSHRKCNA3CA4TAAR1
Diphenylether SCHEMBL11709195 0.73 LTA4H (0.75) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL29065616 0.72 CA4 (0.39) LTA4HTSHRKCNA3CA4ALDH1A1
SCHEMBL10576494 0.72 APP (0.39) LTA4HCA1CA2CA9
SCHEMBL28759416 0.72 LTA4H (0.41) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL7596677 0.71 LTA4H (0.45) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL14472046 0.71 LTA4H (0.45) LTA4HTSHRKCNA3CA4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539448-A Catalyst for olefin polymerization and preparation method and application thereof 北京吉海川科技发展有限公司 2022-05-27 CN claimed
CN-114130212-A Method for preparing separation membrane by using small molecule monomer 天津工业大学 2022-03-04 CN claimed
CN-110407966-B Ultrahigh molecular weight polyethylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2021-08-03 CN claimed
CN-108467442-B Olefin coordination polymerization catalyst and application thereof 中国石油天然气股份有限公司 2021-06-01 CN claimed
EP-3050906-B1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORP LTD (IN) 2020-07-22 EP claimed
EP-3653631-A1 PROCESSES FOR THE PREPARATION OF AN OLEFIN POLYMERIZATION CATALYST BASED ON TREATING SOLID ORGANOMAGNESIUM COMPOUNDS WITH TITANIUM MOIETIES INDIAN OIL CORPORATION Ltd. (IN) 2020-05-20 EP claimed
EP-3018150-B1 PROCESS FOR THE PREPARATION OF SPHERICAL CATALYST PARTICLES INDIAN OIL CORP LTD (IN) 2020-03-11 EP claimed
EP-2966099-B1 PARTICLE SIZE DISTRIBUTION CONTROL THROUGH INTERNAL DONOR IN ZIEGLER-NATTA CATALYST INDIAN OIL CORP LTD (IN) 2020-03-11 EP claimed
EP-3543247-A1 PRECURSOR FOR CATALYST, PROCESS FOR PREPARING THE SAME AND ITS USE THEREOF INDIAN OIL CORPORATION Ltd. (IN) 2019-09-25 EP claimed
US-10100136-B2 Organometallic compound in solid form, process for preparing the same and use thereof INDIAN OIL CORPORATION LIMITED (IN) 2018-10-16 US claimed
EP-0539937-A1 Process for producing olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP claimed
US-4820672-A REACTING MAGNESIUM OR ORGANOMAGNESIUM COMPOUNDS, HYDROGEN CHLORIDE, CHLOROALCOHOL, BETA-ALKYL SUBSTITUTED ALCOHOLS; POLY CAT OR SUPPORTS LITHIUM CORPORATION OF AMERICA (US) 1989-04-11 US claimed
US-4397763-A TITANIUM-BASED PHILLIPS PETROLEUM COMPANY (US) 1983-08-09 US claimed
US-4330648-A MIXTURE OF TITANIUM HALIDE, MAGNESIUM OR MANGANOUS CHLORIDE DIHYDROCARBYLALUMINUM HALIDE OR HYDRIDE AND AN ETHER-ALCOHOL PHILLIPS PETROLEUM COMPANY (US) 1982-05-18 US claimed
US-4312784-A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANOUS CHLORIDE, UNSATURATED HYDROCARBON AND TRIHYDROCARBYLALUMNIUM PHILLIPS PETROLEUM CO. (US) 1982-01-26 US claimed
US-4242480-A TWO OR THREE COMPONENT SYSTEM COMPRISING A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANESE CHLORIDE, UNSATURATED HYDROCARBON, ORGANOALUMINUM COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1980-12-30 US claimed
US-4202953-A MAGNESIUM HALIDE ANHYDRIDE CARRIERS FOR POLYMERIZATION CATALYSTS NIPPON OIL CO., LTD. (JP) 1980-05-13 US claimed
US-4022958-A Process for preparing polyolefins NIPPON OIL COMPANY LTD. (JA) 1977-05-10 US claimed
US-4006101-A Polymerization of olefins and catalysts therefor NIPPON OIL COMPANY LTD. (JA) 1977-02-01 US claimed
US-3991260-A Process for preparing polyolefins NIPPON OIL CORPORATION LTD. (JA) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10100136-B2 Organometallic compound in solid form, process for preparing the same and use thereof MLX, BRIX1, CYP4X1 LTA4H 1162/4885TSHR 2774/4885KCNA3 785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.