Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157572 | 0.93 | P2RX7 (0.50) | P2RX7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30157499 | 0.92 | P2RX7 (0.53) | P2RX7ALDH1A1KDM4ETAAR1MEN1 | |
| SCHEMBL30157510 | 0.92 | P2RX7 (0.51) | P2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL30157682 | 0.92 | ALDH1A1 (0.57) | P2RX7ALDH1A1 | |
| SCHEMBL30157436 | 0.92 | P2RX7 (0.48) | P2RX7ALDH1A1KMT2A | |
| SCHEMBL30157993 | 0.90 | P2RX7 (0.55) | P2RX7ALDH1A1TAAR1KMT2A | |
| SCHEMBL30157794 | 0.90 | P2RX7 (0.55) | P2RX7ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30157834 | 0.90 | P2RX7 (0.47) | P2RX7ALDH1A1KDM4EHDAC1HDAC2 | |
| SCHEMBL30157971 | 0.90 | P2RX7 (0.47) | P2RX7ALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL30158008 | 0.90 | P2RX7 (0.49) | P2RX7ALDH1A1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |