Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157436 | 0.91 | P2RX7 (0.48) | P2RX7ALDH1A1KMT2A | |
| SCHEMBL30157510 | 0.91 | P2RX7 (0.51) | P2RX7TSHRNPSR1HTTALDH1A1 | |
| SCHEMBL30157349 | 0.90 | P2RX7 (0.51) | P2RX7TSHRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30157971 | 0.89 | P2RX7 (0.47) | P2RX7TSHRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30157834 | 0.89 | P2RX7 (0.47) | P2RX7ALDH1A1HDAC1HDAC2 | |
| SCHEMBL30157936 | 0.89 | KDM4E (0.49) | P2RX7MAPTALDH1A1KMT2A | |
| SCHEMBL30157596 | 0.88 | P2RX7 (0.48) | P2RX7ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL30157572 | 0.87 | P2RX7 (0.50) | P2RX7TSHRSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL30157760 | 0.87 | ALDH1A1 (0.48) | P2RX7MAPTALDH1A1 | |
| SCHEMBL30157993 | 0.86 | P2RX7 (0.55) | P2RX7ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |