Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157712 | 0.87 | KMT2A (0.57) | KMT2AALDH1A1KDM4EMAPTGAA | |
| SCHEMBL30157807 | 0.87 | TSHR (0.47) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| SCHEMBL30157731 | 0.84 | KMT2A (0.42) | KMT2AALDH1A1KDM4EMAPTGAA | |
| SCHEMBL30157641 | 0.83 | SLC6A4 (0.48) | KMT2AALDH1A1KDM4EGAAPKM | |
| SCHEMBL30157508 | 0.82 | LMNA (0.40) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL30157628 | 0.80 | EPHX2 (0.44) | KMT2AMEN1HDAC1HDAC2P2RX7 | |
| SCHEMBL30157408 | 0.80 | SIGMAR1 (0.51) | KMT2ALMNAALDH1A1GAAHDAC1 | |
| SCHEMBL30157904 | 0.79 | P2RX7 (0.44) | KMT2ALMNAMEN1ALDH1A1MAPT | |
| SCHEMBL30157737 | 0.79 | EPHX2 (0.56) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL30157493 | 0.78 | P2RX7 (0.54) | KMT2ALMNAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |