SCHEMBL301584

SCHEMBL301584

C[Si](C)(C)OC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
ACHE P22303 1/20 0.33
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
EPHX1 P07099 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16569783 1.00 CA1 (0.33) CA1CA2ACHECA12CA9
SCHEMBL7941245 0.97 ACHE (0.30) ACHE
SCHEMBL8788188 0.84
SCHEMBL1053896 0.82 CA1 (0.33) CA1CA2ACHECA12CA9
SCHEMBL1049096 0.82 CA1 (0.33) CA1CA2ACHECA12CA9
SCHEMBL11121190 0.82 CA1 (0.33) CA1CA2ACHECA12CA9
SCHEMBL14620409 0.79
SCHEMBL15803229 0.79
SCHEMBL11122661 0.79 ACHE (0.30) ACHE
SCHEMBL1704223 0.79 ACHE (0.30) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102482298-B (E) -styryl-alkynyl substituted silicon compounds and method for obtaining (E) -styryl-alkynyl substituted silicon compounds UNIV ADAM MICKIEWICZ 2015-03-11 CN claimed
CN-102482301-B New vinyl-alkynylsubstituted germanium compounds and method to obtain vinyl- alkynylsubstituted germanium compounds UNIV ADAM MICKIEWICZ 2014-07-16 CN claimed
US-8680310-B2 (E)-styryl-alkynylsubstituted silicon compounds and method of obtaining (E)-styryl-alkynylsubstituted silicon compounds ADAM MICKIEWICZ UNIVERSITY (PL) 2014-03-25 US claimed
US-20130260575-A1 SILICON PRECURSORS AND COMPOSITIONS COMPRISING SAME FOR DEPOSITING LOW DIELECTRIC CONSTANT FILMS AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-10-03 US claimed
US-8344169-B2 Vinyl-alkynylsubstituted germanium compounds and method to obtain vinyl-alkynylsubstituted germanium compounds ADAM MICKIEWICZ UNIVERSITY (PL) 2013-01-01 US claimed
EP-2475670-A1 NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS Adam Mickiewicz University (PL) 2012-07-18 EP claimed
EP-2475671-A1 NEW VINYL-ALKYNYLSUBSTITUTED GERMANIUM COMPOUNDS AND METHOD TO OBTAIN VINYL- ALKYNYLSUBSTITUTED GERMANIUM COMPOUNDS Adam Mickiewicz University (PL) 2012-07-18 EP claimed
US-20120178955-A1 NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS ADAM MICKIEWICZ UNIVERSITY (PL) 2012-07-12 US claimed
US-20120178952-A1 NEW VINYL-ALKYNYLSUBSTITUTED GERMANIUM COMPOUNDS AND METHOD TO OBTAIN VINYL-ALKYNYLSUBSTITUTED GERMANIUM COMPOUNDS ADAM MICKIEWICZ UNIVERSITY (PL) 2012-07-12 US claimed
CN-102482298-A Novel -styryl-alkynyl substituted silicon compounds and method for obtaining -styryl-alkynyl substituted silicon compounds UNIV ADAM MICKIEWICZ 2012-05-30 CN claimed
US-6555678-B1 Reacting with a silylating agent, extracting the silylated cellulose from the synthesis reaction medium, spinning through extrusion die(s), and treating the resultant yarn with a desilylation agent to regenerate the celluose and a siloxane RHODIA ACETOW (DE) 2003-04-29 US claimed
EP-1025291-B1 METHOD FOR PREPARING A REGENERATED CELLULOSE FIBRE OR YARN RHODIA ACETOW (DE) 2003-04-09 EP claimed
US-6486328-B1 Substituted 2-[-6-benzyl-5-oxo-3-phenyl-(3s,7s, 7aR)-perhydroimidazol[1,5-c][1,3]thiazol-7yl] compounds COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-11-26 US claimed
EP-1025291-A1 METHOD FOR PREPARING A REGENERATED CELLULOSE FIBRE OR YARN Rhodia Acetow (DE) 2000-08-09 EP claimed
WO-1999022051-A1 METHOD FOR PREPARING A REGENERATED CELLULOSE FIBRE OR YARN RHODIA ACETOW (DE) 1999-05-06 WO claimed
WO-1999021892-A1 METHOD FOR SILYLATING CARBOHYDRATES RHODIA ACETOW (DE) 1999-05-06 WO claimed
EP-0594175-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1997-06-18 EP claimed
US-5391691-A Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP claimed
WO-1994007899-A1 SYNTHESIS OF C-GLYCOSYLATED COMPOUNDS WITH THE USE OF A MILD, IODINE-CATALYZED REACTION THE BOARD OF REGENTS ACTING FOR AND ON BEHALF OF THE UNIVERSITY OF MICHIGAN (US) 1994-04-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178952-A1 NEW VINYL-ALKYNYLSUBSTITUTED GERMANIUM COMPOUNDS AND METHOD TO OBTAIN VINYL-ALKYNYLSUBSTITUTED GERMANIUM COMPOUNDS GMNN, VCL, AGL CA1 3074/4885CA2 2974/4885ACHE 4421/4885
US-20120178955-A1 NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS SPTBN1, TST, SPTAN1 CA1 2138/4885CA2 2137/4885ACHE 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.