Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187852 | 1.00 | PSMD10 (0.37) | PSMD10GPR119TBXA2RCA12CA1 | |
| SCHEMBL30158883 | 0.87 | PSMD10 (0.38) | PSMD10GPR119CA12CA1CA2 | |
| SCHEMBL29187914 | 0.87 | PSMD10 (0.38) | PSMD10GPR119CA12CA1CA2 | |
| SCHEMBL30158952 | 0.85 | PSMD10 (0.39) | PSMD10GPR119CA12CA1CA2 | |
| SCHEMBL29187888 | 0.85 | PSMD10 (0.39) | PSMD10GPR119CA12CA1CA2 | |
| SCHEMBL23970619 | 0.82 | CNR2 (0.35) | GPR119 | |
| SCHEMBL28950629 | 0.81 | ALDH1A1 (0.43) | PSMD10CA12CA1CA9F2 | |
| SCHEMBL30159078 | 0.81 | ALDH1A1 (0.43) | PSMD10CA12CA1CA9F2 | |
| SCHEMBL23970618 | 0.80 | DUT (0.33) | — | |
| SCHEMBL28950578 | 0.79 | PSMD10 (0.38) | PSMD10GPR119TBXA2RCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-A | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2022-12-30 | — | — | CN | disclosed |