Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904651 | 1.00 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 | |
| SCHEMBL18816227 | 0.91 | DGAT2 (0.45) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 | |
| SCHEMBL27032319 | 0.89 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPSR1MAPK1RAB9A | |
| SCHEMBL10324149 | 0.88 | DGAT2 (0.40) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 | |
| SCHEMBL30159592 | 0.88 | DGAT2 (0.40) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 | |
| SCHEMBL29444527 | 0.88 | HCAR3 (0.43) | ALDH1A1DGAT2RAB9AHPGDRXRA | |
| SCHEMBL9904464 | 0.88 | HCAR3 (0.43) | ALDH1A1DGAT2RAB9AHPGDRXRA | |
| SCHEMBL18548025 | 0.87 | DGAT2 (0.40) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 | |
| SCHEMBL30159688 | 0.86 | DGAT2 (0.39) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 | |
| SCHEMBL10324566 | 0.86 | DGAT2 (0.39) | ALDH1A1SMN1; SMN2ATMNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |