SCHEMBL30159652

SCHEMBL30159652

C=C(C)C(=O)OCCOC(=O)C(=C)CS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
RECQL P46063 1/20 0.44
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
PKM P14618 2/20 0.43
MAPT P10636 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA9 Q16790 3/20 0.41
KMT2A Q03164 3/20 0.41
HSD11B1 P28845 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
CA12 O43570 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30159743 0.96 ALDH1A1 (0.46) ALDH1A1RECQLCA2CA1PKM
SCHEMBL17416311 0.96 ALDH1A1 (0.46) ALDH1A1RECQLCA2CA1PKM
SCHEMBL29212198 0.93 TSHR (0.47) ALDH1A1RECQLCA2CA1PKM
SCHEMBL17424801 0.93 TSHR (0.47) ALDH1A1RECQLCA2CA1PKM
SCHEMBL29212208 0.93 TSHR (0.47) ALDH1A1RECQLCA2CA1PKM
SCHEMBL17424797 0.90 ALDH1A1 (0.50) ALDH1A1RECQLCA2CA1PKM
SCHEMBL17424790 0.90 ALDH1A1 (0.50) ALDH1A1RECQLCA2CA1PKM
SCHEMBL17424803 0.87 ALDH1A1 (0.50) ALDH1A1RECQLCA2CA1PKM
SCHEMBL20145427 0.87 ALDH1A1 (0.50) ALDH1A1RECQLCA2CA1PKM
SCHEMBL30159663 0.87 ALDH1A1 (0.44) ALDH1A1RECQLCA2CA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12296031-B2 Esthetic dental filling material with high depth of cure IVOCLAR VIVADENT AG (LI) 2025-05-13 US claimed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US claimed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US claimed
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure IVOCLAR VIVADENT AG (LI) 2023-02-16 US claimed
EP-4124331-A1 AESTHETIC DENTAL FILLING MATERIAL WITH HIGH CURING DEPTH Ivoclar Vivadent AG (LI) 2023-02-01 EP claimed
US-12296031-B2 Esthetic dental filling material with high depth of cure IVOCLAR VIVADENT AG (LI) 2025-05-13 US disclosed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US disclosed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US disclosed
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure IVOCLAR VIVADENT AG (LI) 2023-02-16 US disclosed
EP-4124331-A1 AESTHETIC DENTAL FILLING MATERIAL WITH HIGH CURING DEPTH Ivoclar Vivadent AG (LI) 2023-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885RECQL 1236/4885CA2 3658/4885
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885RECQL 1236/4885CA2 3658/4885
US-12296031-B2 Esthetic dental filling material with high depth of cure RARA, RARG, RARB ALDH1A1 49/4885RECQL 81/4885CA2 3940/4885
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure RARA, RARG, RARB ALDH1A1 49/4885RECQL 81/4885CA2 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.