Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535765 | 1.00 | NOTUM (0.40) | NOTUMBRD4RAB9AALDH1A1HPGD | |
| SCHEMBL30159550 | 0.88 | HCAR3 (0.36) | BRD4KDM4ESCN9A | |
| SCHEMBL23535658 | 0.88 | HCAR3 (0.36) | BRD4KDM4ESCN9A | |
| SCHEMBL30204313 | 0.83 | ALDH1A1 (0.38) | BRD4RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL23535848 | 0.83 | ALDH1A1 (0.41) | NOTUMALDH1A1HPGDSMN1; SMN2KIF11 | |
| SCHEMBL30040748 | 0.83 | ALDH1A1 (0.41) | NOTUMALDH1A1HPGDSMN1; SMN2KIF11 | |
| SCHEMBL23535717 | 0.77 | BRD4 (0.43) | BRD4RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30159531 | 0.77 | BRD4 (0.43) | BRD4RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23559619 | 0.76 | MAP2K4 (0.37) | BRD4RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15081349 | 0.75 | BRD4 (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |