Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535658 | 1.00 | HCAR3 (0.36) | HCAR3BRD4SLC22A12CSNK2A1KDM4E | |
| SCHEMBL30159691 | 0.88 | NOTUM (0.40) | BRD4KDM4ESCN9A | |
| SCHEMBL23535765 | 0.88 | NOTUM (0.40) | BRD4KDM4ESCN9A | |
| SCHEMBL30204864 | 0.82 | HCAR3 (0.39) | HCAR3SLC22A12CSNK2A1TNKSTNKS2 | |
| SCHEMBL30039575 | 0.81 | HCAR3 (0.44) | HCAR3SLC22A12CSNK2A1KDM4ERORC | |
| SCHEMBL23535847 | 0.81 | HCAR3 (0.44) | HCAR3SLC22A12CSNK2A1KDM4ERORC | |
| SCHEMBL15081349 | 0.77 | BRD4 (0.36) | BRD4PAX8HTR2CSLC6A4 | |
| SCHEMBL23535811 | 0.75 | BRD4 (0.41) | HCAR3BRD4SLC22A12RORC | |
| SCHEMBL30159646 | 0.75 | BRD4 (0.41) | HCAR3BRD4SLC22A12RORC | |
| SCHEMBL15081313 | 0.74 | L3MBTL1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4337662-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | Bridge Medicines (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |