Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20046646 | 0.86 | GPR119 (0.47) | GPR119KDM4EPKMUSP2SMN1; SMN2 | |
| SCHEMBL7379091 | 0.85 | ALDH1A1 (0.51) | GPR119KDM4EUSP2SMN1; SMN2MEN1 | |
| SCHEMBL20046615 | 0.84 | GPR119 (0.52) | GPR119KDM4EPKMUSP2SMN1; SMN2 | |
| SCHEMBL20046769 | 0.83 | GPR119 (0.51) | GPR119USP2SMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL23536788 | 0.82 | GPR119 (0.43) | GPR119KDM4EPKMUSP2SMN1; SMN2 | |
| SCHEMBL26828658 | 0.81 | GPR119 (0.50) | GPR119USP2SMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL2941284 | 0.81 | RAB9A (0.51) | GPR119KDM4EMEN1KMT2A | |
| SCHEMBL22645436 | 0.81 | GPR119 (0.49) | GPR119USP2SMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL25141827 | 0.81 | GPR119 (0.49) | GPR119USP2SMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL21679219 | 0.80 | GPR119 (0.53) | GPR119USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077309-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |