Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950740 | 0.71 | PYGM (1.00) | PYGM | |
| SCHEMBL4696617 | 0.69 | PYGM (0.62) | PYGM | |
| SCHEMBL28954912 | 0.68 | ERBB2 (0.33) | KDM4EALDH1A1TSHR | |
| SCHEMBL7430507 | 0.65 | PYGM (0.42) | PYGM | |
| SCHEMBL890639 | 0.63 | PYGM (0.52) | PYGMTP53ALDH1A1DAOTSHR | |
| SCHEMBL8905393 | 0.62 | CFTR (0.50) | DHODHKDM4EKMOALDH1A1DAO | |
| SCHEMBL10384372 | 0.60 | SLC6A2 (0.50) | DHODHKMOALDH1A1DAOTSHR | |
| SCHEMBL1751676 | 0.58 | SLC6A3 (0.65) | DHODH | |
| SCHEMBL1751726 | 0.58 | SLC6A3 (0.60) | DHODH | |
| SCHEMBL4350863 | 0.58 | SLC6A3 (0.65) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024037910-A1 | SYK INHIBITORS FOR USE IN THE TREATMENT OF CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-02-22 | — | — | WO | disclosed |