SCHEMBL3016429

SCHEMBL3016429

Cc1cc(O)ccc1OCC(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VDR P11473 1/20 0.47
KDM4E B2RXH2 3/20 0.46
HPGD P15428 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MEN1 O00255 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
ESR1 P03372 3/20 0.46
CYP2C9 P11712 2/20 0.45
CYP1A2 P05177 1/20 0.45
HIF1A Q16665 1/20 0.45
AR P10275 1/20 0.44
POLB P06746 3/20 0.44
ITGB1 P05556 1/20 0.42
ITGA4 P13612 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
MAPT P10636 4/20 0.42
LMNA P02545 2/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12541603 0.86 MEN1 (0.52) VDRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL1549647 0.84 VDR (0.46) VDRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL28979210 0.84 AAK1 (0.56) VDRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL22777216 0.84 CYP1A2 (0.64) KDM4EHPGDMEN1TSHRKMT2A
SCHEMBL22396845 0.84 NOTUM (0.48) VDRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL26691698 0.83 MAOB (0.44) KDM4EHPGDALDH1A1HSD17B10MEN1
SCHEMBL1245338 0.83 LMNA (0.50) KDM4EHPGDTSHRESR1CYP2C9
SCHEMBL3015438 0.82 MAPT (0.49) VDRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL1549625 0.82 VDR (0.45) VDRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL1549799 0.81 ESR1 (0.61) VDRKDM4EHPGDALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100197950-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HIGH POINT PHARMACEUTICALS, LLC 2010-08-05 US disclosed
EP-2029507-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES High Point Pharmaceuticals, LLC (US) 2009-03-04 EP disclosed
WO-2007141295-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HIGH POINT PHARMACEUTICALS, LLC (US) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197950-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HAAO, HPD, PAH VDR 4294/4885KDM4E 337/4885HPGD 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.