SCHEMBL30164686

SCHEMBL30164686

CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(CC(=O)OC)c3)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5469568 1.00 TLR7 (1.00) TLR7
SCHEMBL5464741 0.92 TLR7 (1.00) TLR7
SCHEMBL5468642 0.92 TLR7 (1.00) TLR7
SCHEMBL31126375 0.91 TLR7 (0.83) TLR7
SCHEMBL20551608 0.91 TLR7 (0.83) TLR7
SCHEMBL5457983 0.90 TLR7 (0.82) TLR7
SCHEMBL5471583 0.90 TLR7 (0.82) TLR7
SCHEMBL5490042 0.90 TLR7 (0.86) TLR7
SCHEMBL4577154 0.90 TLR7 (0.81) TLR7
SCHEMBL24052315 0.89 TLR7 (0.81) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270316-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF TIANJIN LIPOGEN TECH CO LTD (CN) 2025-08-28 US claimed
EP-4559479-A2 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-05-28 EP claimed
CN-117881419-A Pharmaceutical combination and use thereof 天津立博美华基因科技有限责任公司 2024-04-12 CN claimed
WO-2023274275-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF 天津立博美华基因科技有限责任公司 2023-01-05 WO claimed
EP-3568162-B1 MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS NEKTAR THERAPEUTICS (US) 2026-03-18 EP disclosed
EP-4634153-A1 LIPID COMPOUNDS AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2025-10-22 EP disclosed
US-20250270316-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF TIANJIN LIPOGEN TECH CO LTD (CN) 2025-08-28 US disclosed
US-20250249092-A1 CONJUGATE OF CAPRIN-1 ANTIBODY LINKED TO IMMUNE ACTIVATOR FOR CANCER TREATMENT TORAY INDUSTRIES, INC. (JP) 2025-08-07 US disclosed
EP-4559479-A2 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-05-28 EP disclosed
US-12274745-B2 Conjugate of CAPRIN-1 antibody linked to immune activator for cancer treatment TORAY INDUSTRIES, INC. (JP) 2025-04-15 US disclosed
WO-2025059165-A1 METHODS OF USE FOR RHAMM-DERIVED PEPTIDES AND RHAMM-DERIVED PEPTIDE MIMETICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-03-20 WO disclosed
US-20250049951-A1 NUCLEIC ACID COMPOSITIONS AND USES THEREOF SURGE Therapeutics, Inc. 2025-02-13 US disclosed
US-12030940-B2 Immunotherapeutic tumor treatment method NEKTAR THERAPEUTICS (US) 2024-07-09 US disclosed
WO-2024130086-A1 LIPID COMPOUNDS AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-06-20 WO disclosed
US-20230372500-A1 MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS NEKTAR THERAPEUTICS (US) 2023-11-23 US disclosed
CN-116850279-A Reductive adjuvant nano system for relieving adaptive dermatitis and application 浙江大学 2023-10-10 CN disclosed
US-11744898-B2 Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods NEKTAR THERAPEUTICS (US) 2023-09-05 US disclosed
US-20230181743-A1 FUNCTIONAL LIPID DERIVATIVES AND USES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-06-15 US disclosed
EP-4153590-A1 FUNCTIONAL LIPID DERIVATIVES AND USES THEREOF Ohio State Innovation Foundation (US) 2023-03-29 EP disclosed
WO-2023274275-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF 天津立博美华基因科技有限责任公司 2023-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372500-A1 MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS TLR7, TLR8, TLR3 TLR7 1/4885
US-20250049951-A1 NUCLEIC ACID COMPOSITIONS AND USES THEREOF STING1, TLR9, HDGF TLR7 188/4885
US-20230181743-A1 FUNCTIONAL LIPID DERIVATIVES AND USES THEREOF LIPA, LIPG, LIPC TLR7 1104/4885
US-11744898-B2 Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods TLR7, TLR8, TLR3 TLR7 1/4885
US-12030940-B2 Immunotherapeutic tumor treatment method CD274, TLR7, PDCD1LG2 TLR7 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.