Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23884289 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23884322 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23917013 | 0.82 | MEN1 (0.42) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23884309 | 0.80 | LMNA (0.48) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23884320 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23884349 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23900313 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23907981 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23884164 | 0.72 | SCN9A (0.32) | ALDH1A1 | |
| SCHEMBL30165244 | 0.72 | SCN9A (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916175-A | Novel 2-pyrimidinone analogs as potent antiviral agents against alphaviruses | 南方研究院 | 2023-04-04 | — | — | CN | disclosed |
| EP-4125845-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | Southern Research Institute (US) | 2023-02-08 | — | — | EP | disclosed |