Ticlatone

Ticlatone

SCHEMBL30165586

O=c1[nH]sc2cc(Cl)ccc12

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
LMNA P02545 3/20 0.61
MAPT P10636 2/20 0.61
POLB P06746 1/20 0.61
KDM4E B2RXH2 2/20 0.53
DDAH1 O94760 1/20 0.53
CASP3 P42574 1/20 0.53
HTT P42858 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
MAOA P21397 1/20 0.46
DAO P14920 2/20 0.46
PARP1 P09874 1/20 0.43
BCKDK O14874 1/20 0.40
MCL1 Q07820 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ticlatone SCHEMBL193888 1.00 ALDH1A1 (0.61) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL79949 0.84 LMNA (0.53) ALDH1A1LMNAMAPTPOLBKDM4E
Ticlatone SCHEMBL8847872 0.78 ALDH1A1 (0.40) ALDH1A1LMNAMAPTPOLBKDM4E
Ticlatone SCHEMBL8621502 0.77 ALDH1A1 (0.40) ALDH1A1LMNAMAPTPOLBKDM4E
Ticlatone SCHEMBL6657359 0.76 ALDH1A1 (0.39) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL11737600 0.76 ALDH1A1 (0.61) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL5807922 0.76 ALDH1A1 (0.61) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL81346 0.76 ALDH1A1 (0.61) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL13455388 0.76 ALDH1A1 (0.61) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL8130952 0.76 ALDH1A1 (1.00) ALDH1A1LMNAMAPTPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119789870-A Multicomponent pharmaceutical compositions and kits containing nitric oxide releasing compounds and methods of use thereof 诺欧生物有限责任公司 2025-04-08 CN disclosed
CN-119136833-A Membrane translocation domain and uses thereof 俄亥俄州创新基金会 2024-12-13 CN disclosed
EP-4110330-A1 ANTI-VIRAL COMPOUNDS AND METHODS FOR ADMINISTRATION THEREOF Gregg, John Malcolm Hall (US) 2023-01-04 EP disclosed