Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645428 | 0.84 | MAPT (0.53) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL8130952 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| Ticlatone SCHEMBL30165586 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL5807922 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| Ticlatone SCHEMBL193888 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL13455388 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL15680252 | 0.75 | MAOA (0.53) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL11541846 | 0.73 | PARP15 (0.46) | ALDH1A1MAPTPOLBKDM4EHTT | |
| SCHEMBL25828724 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL25834539 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110711496-B | Anti-biological-pollution porous membrane and preparation method and application thereof | 东莞东阳光科研发有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-110711496-A | Anti-biological-pollution porous membrane and preparation method and application thereof | 东莞东阳光科研发有限公司 | 2020-01-21 | — | — | CN | disclosed |
| US-9662328-B2 | Targeting human thymidylate kinase induces DNA repair toxicity in malignant tumor cells | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-05-30 | — | — | US | disclosed |
| US-20160290036-A1 | HEAT-SHIELDING MATERIAL AND WINDOW GLASS | FUJIFILM CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20160290036-A1 | HEAT-SHIELDING MATERIAL AND WINDOW GLASS | FUJIFILM CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20160151362-A1 | TARGETING HUMAN THYMIDYLATE KINASE INDUCES DNA REPAIR TOXICITY IN MALIGNANT TUMOR CELLS | NATIONAL TAIWAN UNIVERSITY (TW) | 2016-06-02 | — | — | US | disclosed |
| US-8129308-B2 | Thermal transfer image-receiving sheet and surface condition improver | FUJIFILM CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129308-B2 | Thermal transfer image-receiving sheet and surface condition improver | FUJIFILM CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090087552-A1 | METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20090087552-A1 | METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-2042334-A2 | Method of producing heat-sensitive transfer image-receiving sheet | Fujifilm Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-20090011154-A1 | THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER | FUJIFILM CORPORATION (JP) | 2009-01-08 | — | — | US | disclosed |
| US-20090011154-A1 | THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER | FUJIFILM CORPORATION (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1974946-A1 | Thermal transfer image-receiving sheet and surface condition improver | FUJIFILM Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-0235449-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0235449-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160151362-A1 | TARGETING HUMAN THYMIDYLATE KINASE INDUCES DNA REPAIR TOXICITY IN MALIGNANT TUMOR CELLS | DTYMK, TYMP, TK1 | ALDH1A1 1743/4885MAPT 2559/4885LMNA 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.