Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.40 |
| ▸ | PRKDC | P78527 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039919 | 0.78 | JAK3 (0.41) | LCKJAK3BTKHRH3 | |
| SCHEMBL29931205 | 0.77 | JAK3 (0.59) | LCKJAK3BTK | |
| SCHEMBL28647032 | 0.77 | JAK3 (0.59) | LCKJAK3BTK | |
| SCHEMBL30165882 | 0.76 | LCK (0.40) | LCKJAK3BTKHRH3 | |
| SCHEMBL30160837 | 0.76 | JAK3 (0.51) | LCKJAK3BTK | |
| SCHEMBL30161265 | 0.76 | JAK3 (0.46) | LCKJAK3BTKHRH3 | |
| SCHEMBL30161258 | 0.75 | LCK (0.43) | LCKJAK3BTKHRH3 | |
| SCHEMBL30160867 | 0.75 | JAK3 (0.42) | LCKJAK3BTKHRH3 | |
| SCHEMBL30160933 | 0.75 | JAK3 (0.42) | LCKJAK3BTKHRH3 | |
| SCHEMBL30160878 | 0.74 | LCK (0.42) | LCKJAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-B | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |