Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.52 |
| ▸ | NPC1 | O15118 | 14/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28900144 | 1.00 | RAB9A (0.52) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28466081 | 0.85 | RAB9A (0.64) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL30166758 | 0.85 | RAB9A (0.64) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28463241 | 0.84 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL30166727 | 0.84 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28945548 | 0.72 | CASP3 (0.73) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL30166755 | 0.69 | RAB9A (0.78) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28462219 | 0.69 | RAB9A (0.78) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL16334021 | 0.68 | RAB9A (0.87) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL24812486 | 0.68 | MEN1 (0.69) | RAB9ANPC1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812111-B | Benzothiazole compound and medical application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |