Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.64 |
| ▸ | NPC1 | O15118 | 11/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.59 |
| ▸ | CASP3 | P42574 | 3/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466081 | 1.00 | RAB9A (0.64) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL28945548 | 0.86 | CASP3 (0.73) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL30166718 | 0.85 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL28900144 | 0.85 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL24812486 | 0.83 | MEN1 (0.69) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL30166699 | 0.83 | MEN1 (0.69) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL28462219 | 0.83 | RAB9A (0.78) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL30166755 | 0.83 | RAB9A (0.78) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL16334021 | 0.82 | RAB9A (0.87) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL30166708 | 0.81 | RAB9A (0.62) | RAB9ANPC1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812111-B | Benzothiazole compound and medical application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |